Primary prevention of Clostridium difficile colitis with a probiotic- Pierre-Jean Maziade MD1
During the year 2003, many care centers in the province of Quebec experienced an increase in the morbidity and mortality rates due to Clostridium difficile-associated diarrhea. The Centre hospitalier Pierre-Le Gardeur was one of them. We had established a good program in prevention of infections in 1998 and since 2001 we also had a pharmacovigilance committee restricting the prescription of antibiotics. In spite of these measures, we were not able to control the outbreak. On February 1st 2004, we decided to administer Bio-K+® CL1285®, a probiotic, to all inpatients on antibiotics. After one month of utilisation, the outbreak was under control.
To read the study please click Maziade-Probiotic_and_C.difficile_Study.pdf
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